Which nutrient is most closely linked to collagen synthesis and wound healing?

Which nutrient is most closely linked to collagen synthesis and wound healing?

• A. Iron
• B. Vitamin C
• C. Vitamin A
• D. Potassium

Answer: (B)

Vitamin C is essential for collagen synthesis and wound healing because it acts as a cofactor for the enzymes that hydroxylate proline and lysine in collagen. This hydroxylation is necessary for the collagen triple helix to form and for the fibers to cross-link, giving tensile strength to new tissue. Without adequate vitamin C, collagen production is impaired, leading to weaker wounds and slower healing—classic signs seen in scurvy. Iron supports oxygen transport and some enzymatic reactions, which aid healing but don’t directly drive collagen cross-linking. Vitamin A helps with epithelialization, and potassium isn’t directly involved in collagen synthesis.