Which factor is a risk factor for skin cancer development?

Which factor is a risk factor for skin cancer development?

• A. Regular use of sunscreen
• B. UV exposure
• C. Moderate sun exposure
• D. Daily use of protective clothing

Answer: (B)

Ultraviolet radiation from the sun is a risk factor for skin cancer because it damages the DNA in skin cells, leading to mutations that can drive cancer development. UVB directly harms DNA, forming mutations like thymine dimers, while UVA generates reactive oxygen species that cause indirect DNA damage. The risk increases with greater and longer cumulative exposure over a lifetime. Protective measures that reduce UV exposure, such as regular sunscreen use, wearing protective clothing daily, and seeking shade, decrease this risk. Moderate sun exposure implies less intense exposure and does not contribute to risk in the same way as unprotected, extensive UV exposure.